Overview
Crohn’s often hides in the mid-jejunum or ileum, regions not easily reached by colonoscopy. Capsule imaging allows gastroenterologists to locate inflammation, guide biologic therapy, and monitor mucosal healing.
Benefits Over Imaging Modalities
Modality |
Radiation |
View of Mucosa |
Patient Comfort |
Cost* |
CT Enterography |
Yes |
Indirect |
IV contrast |
$$ |
MR Enterography |
No |
Indirect |
IV contrast, prolonged scan |
$$$ |
Capsule Endoscopy |
No |
Direct |
Pill ingestion |
$$ |
*Approximate relative scale for the U.S. market.
Use Cases
- Assess disease extent before initiating biologics.
- Confirm mucosal healing at six-month intervals.
- Detect post-surgical recurrence at anastomotic sites.
Safety Considerations
Strictures raise the risk of capsule retention. A dissolvable patency capsule helps confirm safe transit.
Key Takeaways
- Direct visualization trumps surrogate markers like CRP alone.
- Objective mucosal healing correlates with reduced hospitalizations.
- Non-invasive monitoring supports shared decision-making between patient and provider.